NOVEL MONOCLONAL ANTIBODY, AND USE THEREOF

专利名称：NOVEL MONOCLONAL ANTIBODY, AND USE

THEREOF

发明人：HAMAKUBO, TAKAO,MOCHIZUKI,

YASUHIRO,ABURATANI,

HIROYUKI,IWANARI, HIROKO,NIWA,SHUNSUKE,NAKADA, YOSHIKO

申请号：EP10743590申请日：20100220公开号：EP2399934A4公开日：20130320

摘要：[Theme] To provide a monoclonal antibody against human GPR87. Also, toprovide a novel means for diagnosing or treating a malignant tumor. [Solution means]Monoclonal antibodies against human GPR87 are provided. The antibodies can recognizehuman GPR87, which is expressed on a cell membrane while retaining a three-dimensionalstructure, and can recognize GPR87, which is expressed in a cell endogenously with anepitope being present in an extracellular domain of full-length human GPR87. Theantibodies are thus useful in biochemical analysis, etc., of GPR87, useful in

immunohistological diagnosis, etc., of squamous cell carcinoma, and also potentiallyuseful in PET diagnosis, antibodies for treatment, etc., of squamous cell carcinoma.

申请人：THE UNIVERSITY OF TOKYO,PERSEUS PROTEOMICS INC.

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