NOVEL MONOCLONAL ANTIBODY BINDING SPECIFICALLY TO

专利名称：NOVEL MONOCLONAL ANTIBODY BINDING

SPECIFICALLY TO DLL4 AND USE THEREOF

发明人：KIM, EUN A,PARK, SANG KYUNG,MOON,

KYUNG DUK,LEE, DONG HEON,CHOI, YUBIN,KIM, DONG IN,KANG, KYUNG JAE

申请号：EP13813388申请日：20130702公开号：EP2867259A4公开日：20160224

摘要：The present invention relates to a novel monoclonal antibody that bindsspecifically to delta-like ligand (DLL4), and more particularly to a monoclonal antibodythat binds specifically to human delta-like ligand 4 to effectively inhibit the interactionbetween delta-like ligand 4 and Notch receptor, a polynucleotide encoding themonoclonal antibody, an expression vector comprising the polynucleotide, a

transformant comprising the expression vector, a method for preparing the monoclonalantibody, a pharmaceutical composition for preventing or treating cancer comprising themonoclonal antibody, a composition for diagnosing cancer comprising the monoclonalantibody, a method for diagnosing cancer using the monoclonal antibody, and apharmaceutical composition for preventing or treating autoimmune disease comprisingthe monoclonal antibody.

申请人：HANWHA CHEMICAL CORPORATION

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