专利名称：METHOD FOR PRETREATMENT OF
BIOLOGICAL SAMPLE
发明人：Toshiya MATSUBARA申请号：US17264887申请日：20180918
公开号：US20210302286A1公开日：20210930
专利附图：
摘要：The present invention provides a method for pretreatment of a biologicalsample in order to measure a protein contained in the biological sample by liquidchromatography/mass spectrometry. The method includes the step of adding an acetic
acid aqueous solution to the biological sample, so as to prepare a pretreatment samplecontaining an acetic acid at a concentration ranging from 20 to 50 weight percent, bothinclusive. In the present invention, a target protein contained in a biological sample is lessprone to be adsorbed to a sample container, thereby resulting in an increased sensitivityof measuring the protein in the biological sample by mass spectrometry. Further,reproducibility of results of the mass spectrometry is improved, and reliability isincreased.
申请人：SHIMADZU CORPORATION
地址：Kyoto-shi, Kyoto JP
国籍：JP
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