专利名称：Cyclic inhibitors of 11BETA-hydroxysteroid
dehydrogenase 1
发明人：David A. Claremon,Linghang Zhuang,Katerina
Leftheris,Colin M. Tice,Yuanjie Ye,Suresh B.Singh,Frank Himmelsbach
申请号：US12990296申请日：20090430公开号：US08592410B2公开日：20131126
摘要：This invention relates to novel compounds of the Formula Il Ik, Im, Im, Im, In, In,In, lo, lo, lo, Ip, Ip, pharmaceutically acceptable salts thereof, and pharmaceuticalcompositions thereof, which are useful for the therapeutic treatment of diseasesassociated with the modulation or inhibition of 11β-HSD1 in mammals. The inventionfurther relates to pharmaceutical compositions of the novel compounds and methods fortheir use in the reduction or control of the production of Cortisol in a cell or theinhibition of the conversion of cortisone to Cortisol in a cell.
申请人：David A. Claremon,Linghang Zhuang,Katerina Leftheris,Colin M. Tice,YuanjieYe,Suresh B. Singh,Frank Himmelsbach
地址：Maple Glen PA US,Chalfont PA US,Skillman NJ US,Ambler PA US,Ambler PAUS,Kendall Park NJ US,Mittelbiberach DE
国籍：US,US,US,US,US,US,DE
代理机构：McCarter & English LLP
代理人：Steven G. Davis,Michael J. DeGrazia
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